李乾 教授/硕士生导师
全讯白菜网站
全讯白菜策略/铀矿冶生物技术国防重点学科实验室
研究方向:铀矿冶生物技术
E-mail: liqianusc@126.com
1、个人简介:
李乾,男,1984年生,湖南湘乡人,博士,教授,硕士生导师,美国俄克拉荷马大学访问学者。长期致力于铀矿冶生物技术方面的研究,主要从事微生物浸铀技术、放射性废弃物的生物钝化与固化、放射性污染的生物防治等方面的科研工作;主持科研项目9项,其中主持国家自然科学基金2项、湖南省自然科学基金2项、中国博士后科研基金1项;参与科研项目9项,其中国家级科研项目6项(国自科重点项目1项)、省部级科研项目3项;指导研究生创新项目1项、老员工创新项目4项;共发表学术论文40余篇,SCI 检索25篇,EI 检索3篇;授权专利3项。目前主讲《核工业生物学》、《工程化学与放射性化学》、《文献检索与科研写作》、《磁重分选》等课程。
2、教育经历:
2009/09-2012/06,中南大学,资源加工与生物工程学院,生物工程专业,理学博士
2006/09-2009/06,中南大学,资源加工与生物工程学院,微生物学专业,理学硕士
2002/09-2006/06,湖南农业大学,植物保护公司,植物保护专业,农学学士
3、科研、学术与工作经历:
2024/01-至今,全讯白菜网站,全讯白菜策略,教授
2019/6-2021/11,全讯白菜网站,全讯白菜策略,学科科研与研究生办主任
2017/07-2018/07,美国俄克拉荷马大学,环境基因组研究所,访问学者
2013/05-2017/06, 全讯白菜网站矿业工程博士后流动站,博士后,合作导师:丁德馨教授
2016/01-2023/12,全讯白菜网站,全讯白菜策略,副教授
2012/07-2015/12,全讯白菜网站,全讯白菜策略,讲师
4、所承担科研项目:
[1] 国家自然科学基金面上项目:铁氧化细菌介导酸性铀尾砂脉石蚀变稳定尾砂中铀及其长效机制研究(52374172),2024.1-2027.12,50万元,主持;
[2] 国家自然科学基金青年科学项目:铀矿石U/Fe/S物相对铁硫氧化细菌菌群浸矿行为的引导作用机制研究(51804165),2019.1-2021.12,26万元,主持;
[3] 湖南省自然科学基金青年项目:能源基质对铁硫氧化细菌菌群浸铀行为的引导作用机制研究(2018JJ3441),2018.1-2020.12,5万元,主持;
[4] 湖南省自然科学基金青年人才培养联合项目:微生物浸矿体系的菌种合理搭配及其再生机制研究(14JJ6024),2014.1-2016.12,3万元,主持;
[5] 中国博士后科学基金:组合微生物群落的浸铀性能及其协同作用机理研究(2014M562116),2014.1-2016.12,5万元,主持;
[6] 全讯白菜网站留学归国科研启动基金:铀矿石U/Fe/S配比对铁硫氧化细菌菌群浸矿行为的引导作用机制(2018XQD27),2019.1-2021.12,5万元,主持;
[7] 全讯白菜网站博士科研启动基金:基于基因组水平的多种浸矿微生物组合协同抗氟的分子机理研究(2012XQD05),2013.1-2015.12,10万元,主持;
[8] 湖南省教育厅科学研究一般项目:浸矿微生物共培养体系的构建及其协同效应研究(13C821),2013.9-2015.12,1万元,主持;
[9] 中南大学优博扶植基金:低品位铀矿生物柱浸/堆浸体系的浸出动力学研究与微生物群落动态分析(2011ybjz041),2011.6-2012.6,1.5万元,主持;
[10] 国家自然科学基金面上项目:氧纳米气泡在砂岩铀储层中的迁移-转化-反应耦合动力学研究(52374126),2024.1-2027.12,50万元,参与(第二);
[11] 湖南省教育厅优秀青年项目:AHL信号分子驱动下希瓦氏菌生物膜电极富集水中铀的群体感应机制(22B0438),2023.1-2025.12,6万元,参与(第二);
[12] 国家自然科学基金面上项目:生物浸矿过程微生物的高密度培育(51274268),2013.1-2016.12,60万元,参与(第二);
[13] 湖南省教育厅重点项目:氧化型铜尾砂的黑曲霉制粒浸出机理(13A083),2013.9-2016.12,8万元,参与(第二);
[14] 国家自然科学基金面上项目:黑曲霉浸铀过程中生物矿石颗粒的形成及其浸出机理(51674146),2017/01-2020/12,62万元,参与(第三);
[15] 国家自然科学基金面上项目:CO2+O2地浸采铀过程中胶体的形成机制及其对浸铀的影响(11675072),2017/01-2020/12,64万元,参与(第三);
[16] 湖南省科技计划重点项目:核纯BeF2的制备与纯化工艺试验研究(2013GK2023),2013.1-2015.12,20万元,参与(第三);
[17] 国家自然科学基金重点项目:粤北铀尾矿库及周边地区放射性污染产生机制及控制原理(U1401231),2015.1-2018.12,250万元,参与(第六);
[18] 国家自然科学基金面上项目:微生物协同作用浸出底泥重金属的分子机制(51174239),2012.1-2015.12,60万元,参与(第七)。
5、发表论文:
[1] Qian Li *, Yu Yang, Jinfang Ma, Jing Sun, Guangyue Li, Ruiyong Zhang*, Zhao Cui, Ting Li, Xiaobei Liu. Sulfur enhancement effects for uranium bioleaching in column reactors from a refractory uranium ore. Frontiers in Microbiology. 2023, 14:1107649. doi: 10.3389/fmicb.2023.1107649. (IF=6.064)
[2] Jing Sun1, Jinfang Ma1, Qian Li *, Guangyue Li, Wenge Shi, Yu Yang, Pengfei Hu, Zhimin Guo. Role of Fe/S ratios in the enhancement of uranium bioleaching from a complex uranium ore by Acidithiobacillus ferrooxidans and Acidithiobacillus thiooxidans consortium. Journal of Central South University, 2022, 29(12): 3858-3869. (IF=4.4, 中国科技卓越期刊)
[3] Qian Li*, Xiaobei Liu, Jinfang Ma, Jing Sun, Guangyue Li, Zhao Cui, Ting Li. Bidirectional effects of sulfur-oxidizer Acidithiobacillus thiooxidans in uranium bioleaching systems with or without sulfur by mixed acidophilic bacteria. Journal of Radioanalytical and Nuclear Chemistry, 2023, 332: 1787-1794. (IF=1.6)
[4] Yu Yang, Qian Li *, Guangyue Li, Jinfang Ma, Jing Sun, Xiaobei Liu, Zhao Cui, Ting Li. Depth-induced deviation of column bioleaching for uranium embedded in granite porphyry by defined mixed acidophilic bacteria. Journal of Radioanalytical and Nuclear Chemistry, 2022, 331: 3681-3692.
[5] Zhuanming Chen, Qian Li *, Yu Yang, Jing Sun, Guangyue Li, Xiaobei Liu, Shuxia Shu, Xin Li, Haoming Liao. Uranium removal from a radioactive contaminated soil by defined bioleaching bacteria. Journal of Radioanalytical and Nuclear Chemistry, 2022, 331: 439-449.
[6] Qian Li*, Jing Sun, Dexin Ding*, Qingliang Wang, Wenge Shi, Eming Hu, Xingxing Wang, Xiaoyu Jiang. Characterization and uranium bioleaching performance of mixed iron- and sulfur-oxidizers versus iron-oxidizers. Journal of Radioanalytical and Nuclear Chemistry, 2017, 314(3): 1939-1946.
[7] Qian Li, Dexin Ding, Jing Sun, Qingliang Wang, Eming Hu, Wenge Shi, Liyuan Ma, Xue Guo, Xueduan Liu*. Community dynamics and function variation of a defined mixed bioleaching acidophilic bacterial consortium in the presence of fluoride. Annals of Microbiology, 2015, 65(1): 121-128. (IF=1.528)
[8] Guanzhou Qiu*,1, Qian Li1, Runlan Yu, Zhanxue Sun, Yajie Liu, Miao Chen, Huaqun Yin, Yage Zhang, Yili Liang, Lingling Xu, Limin Sun, Xueduan Liu*. Column bioleaching of uranium embedded in granite porphyry by a mesophilic acidophilic consortium. Bioresource Technology. 2011, 102(7): 4697-4702. (IF=9.642)
[9] Qian Li, Youhua Ren, Guanzhou Qiu, Nuo Li, Hongwei Liu, Zhimin Dai, Xian Fu, Li Shen, Yili Liang, Huaqun Yin, Xueduan Liu*. Insights into the pH up-shift responsive mechanism of Acidithiobacillus ferrooxidans by microarray transcriptome profiling. Folia Microbiologica. 2011, 56(5): 439-451. (IF=1.730)
[10] Qian Li, Li Shen, Hailang Luo, Huaqun Yin, Liqin Liao, Guanzhou Qiu*, Xueduan Liu*. Development and evaluation of whole-genome oligonucleotide array for Acidithiobacillus ferrooxidans ATCC 23270. Transactions of Nonferrous Metals Society of China. 2008, 18(6): 1343-1351. (JCR1区, IF=2.615)
[11] 李乾,刘建东,孙静,李会娟,雷治武,胡鹏飞,郭志敏. 矿物加工工程专业科创活动驱导《磁重分选》翻转课堂高效运转. 教育现代化, 2022, 9(21): 88-91.
[12] 李乾*, 蒋潇宇, 王星星, 王清良, 胡鄂明, 史文革. 组合浸矿细菌菌群的氧化特性及其群落结构分析. 全讯白菜网站学报(自然科学版), 2017, 31(3): 25-29.
[13] 李乾,孙静,丁德馨,王清良,马丽媛,刘学端. 浸矿微生物共培养体系在氟胁迫下的基因调控机理探索. 全讯白菜网站学报(自然科学版),2015, 29(3): 14-20.
[14] 李乾,丁德馨,王清良,史文革,胡鄂明,李会娟,马丽媛,肖云花,曹杨,刘学端*. 五种典型浸矿微生物的耐氟性状对比研究. 全讯白菜网站学报(自然科学版),2013,27(2): 16-22.
[15] 杨雨, 李乾*, 马晋芳, 孙静, 李广悦, 刘晓蓓. 某铀矿细菌菌群柱浸过程中的硫强化作用及其机理分析. 全讯白菜网站学报(自然科学版), 2022, 36(4): 17-25.
[16] 马晋芳, 李乾*, 孙静, 杨雨, 蒋熊睿, 曾海滨, 李广悦, 史文革. 某低品位铀矿微生物柱浸试验及其菌群分布规律分析. 矿业研究与开发, 2021, 41(11): 138-143.
[17] 马晋芳,李乾*,孙静,杨雨,李广悦,史文革. Fe/S质量比对铁硫氧化细菌菌群浸铀行为的影响及其作用机制. 全讯白菜网站学报(自然科学版), 2021, 35(4): 22-28.
[18] 李乾,丁德馨,王清良,胡鄂明,史文革,马丽媛,刘学端*. 浸矿微生物共培养体系的耐氟特性及其在氟胁迫下的群落动态分析. 中国有色金属学报,2014, 24(6): 1678-1684. (EI源刊,中国科技卓越期刊)
[19] Jing Sun, Qian Li, Ting Li, Keling Xu, Zhao Cui, Guangyue Li*. Insights into formation and dissolution mechanism of bio-ore pellets in the one-step uranium leaching process by Aspergillus niger. Minerals Engineering, 2022, 184: 107672. (JCR1区, IF=4.8)
[20] Jing Sun, Guangyue Li*, Qian Li, Yongdong Wang, Jianhong Ma, Caiyan Pang, Jing Ma. Impacts of operational parameters on the morphological structure and uranium bioleaching performance of bio-ore pellets in one-step bioleaching by Aspergillus niger. Hydrometallurgy, 2020, 195: 105378. (JCR1区, IF=4.7)
[21] Zhimin Guo, Jiandong Liu, Qian Li, Zhiwu Lei, You Zhou, Pengfei Hu. Effect of surface heterogeneities on interactions between air bubbles and heterogeneous surfaces. Langmuir, 2022, 38(32): 9908-9916.
[22] Ting Li, Zhao Cui, Jing Sun, Qian Li, Yongdong Wang, Guangyue Li. Oxidative capacity of oxygen nanobubbles and their mechanism for the catalytic oxidation of ferrous ions with copper as a catalyst in sulfuric acid medium. Langmuir, 2023, 39(29): 10112-10121.
[23] Guangyue Li*, Jing Sun, Fangyan Li, Yongdong Wang, Qian Li. Macroparticle-enhanced bioleaching of uranium using Aspergillus niger. Minerals Engineering. 2022, 180: 107493. (JCR1区, IF=4.8)
[24] Liyuan Ma, Qian Li, Li Shen, Xue Feng, Yunhua Xiao, Jiemeng Tao, Yili Liang, Huaqun Yin, Xueduan Liu*. Insights into the fluoride-resistant regulation mechanism of Acidithiobacillus ferrooxidans ATCC 23270 based on whole genome microarrays. Journal of Industrial Microbiology and Biotechnology, 2016, 43(10): 1441-1453. (IF=2.824)
[25] Jing Sun, Qian Li, Yongdong Wang, Zhixiang Zhou, Dexin Ding. Isolation of a strain of Penicillium funiculosum and mutational improvement for UO22+ adsorption. Journal of Radioanalytical and Nuclear Chemistry, 2015, 303(1):427-432. (IF=1.137)
[26] 熊骁,王清良,李乾,胡鄂明,冯志钢,李中,王星星,Fe(OH)3胶体对铀的吸附行为,原子能科学技术,2016,1:39-45. (EI)
[27] 张琪, 王清良, 李乾, 胡鄂明, 张洪灿, 杨敬. Al(OH)3 胶体的制备及其对铀的吸附机理. 化工学报,2014, 65(4): 1279-1286. (EI)
[28] 王清良, 李中, 李乾, 胡鄂明, 熊骁, 成泉辉. 新疆某铍精矿浸出工艺研究. 金属矿山, 2014, 9: 69-71.
[29] 李中, 王清良, 李乾, 胡鄂明, 熊骁, 肖吉昌, 成泉辉. 氢氧化铍中硫酸根去除试验研究. 矿冶工程, 2014, 34(4): 83-86.
[30] Runlan Yu*, Jing Liu, An Chen, Daili Zhong, Qian Li, Wenqing Qin, Guanzhou Qiu, Guohua Gu. Interaction mechanism of Cu2+, Fe3+ ions and extracellular polymeric substances during bioleaching chalcopyrite by Acidithiobacillus ferrooxidans ATCC2370. Transactions of Nonferrous Metals Society of China. 2013, 23(1): 231-236. (IF=2.615)
[31] Zhijun Peng, Runlan Yu*, Guanzhou Qiu, Wenqing Qin, Guohua Gu, Qingliang Wang, Qian Li, Xueduan Liu. Really active form of fluorine toxicity affecting Acidithiobacillus ferrooxidans activity in bioleaching uranium. Transactions of Nonferrous Metals Society of China. 2013, 23(3): 812-817. (JCR1区, IF=2.615)
[32] Qihou Li, Nuo Li, Xueduan Liu*, Zhijun Zhou, Qian Li, Yun Fang, Xiangru Fan, Xian Fu, Yi Liu, Huaqun Yin*. Characterization of the acid stress response of Acidithiobacillus ferrooxidans ATCC 23270 based on the method of microarray. Journal of Biological Research-Thessaloniki. 2012, 17: 3-15. (IF=2.121)
[33] Zhijun Zhou,Yun Fang, Qihou Li, Huaqun Yin, Wenqing Qin, Yili Liang, Qian Li, Nuo Li, Xinxing Liu, Guanzhou Qiu, Xueduan Liu*. Global transcriptional analysis of stress-response strategies in Acidithiobacillus ferrooxidans ATCC 23270 exposed to organic extractant - Lix984n. World Journal of Microbiology and Biotechnology. 2012, 28: 1045-1055. (IF=2.477)
[34] Huaqun Yin, Min Tang, Zhijun Zhou, Xian Fu, Li Shen, Yili Liang, Qian Li, Hongwei Liu, Xueduan Liu*. Distinctive heat-shock response of bioleaching microorganism Acidithiobacillus ferrooxidans observed using genome-wide microarray. Canadian Journal of Microbiology, 2012, 58(5): 628-636. (IF=1.793)
[35] Hongwei Liu, Huaqun Yin, Yanxia Dai, Zhimin Dai, Yi Liu, Qian Li, Huidan Jiang, Xueduan Liu*. The co-culture of Acidithiobacillus ferrooxidans and Acidiphilium acidophilum enhances the growth, iron oxidation, and CO2 fixation. Archives of Microbiology. 2011, 193(12): 857-866. (IF=1.884)
[36] Hailang Luo, Li Shen, Huaqun Yin, Qian Li, Qijiong Chen, Yanjie Luo, Liqin Liao, Xueduan Liu*. Comparative genomic analysis of Acidithiobacillus ferrooxidans strains using the A. ferrooxidans ATCC 23270 whole-genome oligonucleotide microarray. Canadian Journal of Microbiology. 2009, 55: 587-598. (IF=1.793)
[37] Liqin Liao, Jun Liu, Yanxia Dai, Qian Li, Ming Xie, Huaqun Yin, Guanzhou Qiu, Xueduan Liu*. Development and application of SCAR markers for sex identification in the dioecious species Ginkgo biloba L. Euphytica. 2009, 169: 49-55. (IF=1.614)
[38] 吴黎武,吉宏斌,王清良,曹振,胡鄂明,李乾. 新疆某铀矿石浸出性能探索性试验研究. 铀矿冶, 2013, (3): 133-137.
[39] 吴学玲, 金德才, 赵维良, 梁任星, 李乾, 杨宇, 邱冠周*. 4株邻苯二甲酸二丁酯降解菌的分离鉴定及其相关降解基因的克隆. 环境科学, 2009, 30(9): 2722-2727.
会议论文4篇:
[40] 马晋芳,李乾*,孙静,杨雨,李广悦,史文革. Fe/S比对铁硫氧化细菌菌群浸铀行为的影响及其作用机制. 第四届全国低品位矿产资源高效利用新技术交流会, 12.8-12.10, 2020, 郑州, 中国
[41] Qian Li, Huaqun Yin, Miao Chen, Runlan Yu, Zhanxue Sun, Yajie Liu, Yage Zhang, Guanzhou Qiu*, Xueduan Liu*. Influence of different acid pre-leaching levels on uranium bioleaching performance in column reactors. The 19th International Biohydrometallurgy Symposium, Sep 17-25, 2011, Changsha, China
[42] Liyuan Ma, Qian Li, Yunhua Xiao, Qingliang Wang, Huaqun Yin, Yili Liang, Guanzhou Qiu , Xueduan Liu*. Comparative study of fluoride-tolerance of five typical bioleaching microorganisms. The 20th International Biohydrometallurgy Symposium, Oct 8-11, 2013, Antofagasta, Chile
[43] 王清良*,李乾,张洪灿,胡鄂明,陈勇博. 酸法地浸采铀污染地下水的化学-生物法联合治理研究. 中国核学会2013年学术年会,9.10-9.13,2013,哈尔滨,中国
6、授权专利:
[44] 一种难浸铀矿石细菌浸出的方法(国家发明), 专利号:ZL 202111294058.8,授权公告日:2023-6-27(第1)(李乾; 孙静; 李广悦; 杨宇; 马晋芳)
[45] 飞行式旋风除尘装置,专利号:ZL201922133104.0,授权公告日:2021-2-2(第1)(李乾; 陈转明; 屈宇琛; 戴薇; 张利强)
[46] A method of rapid oxidating Fe2+ from uranium leachate at low temperature in-situ leaching system by psychrophilic acidophilic bacteria(澳大利亚专利),专利号:2020101726,授权公告日:2020-9-2(第3)(王清良,胡鄂明,李乾,陈鹏,王红强,阳奕汉,徐益群,李德,于长贵,李鹏)
7、出版专著、教材:
[47] 细菌浸铀理论与实践(专著),中国原子能出版社,2019年10月,合著(第3)